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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
10.61
Human Site:
T48
Identified Species:
15.56
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
T48
Q
E
N
E
R
K
G
T
A
R
F
G
H
E
G
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
T107
Q
E
N
E
R
K
G
T
A
R
F
G
H
E
G
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
T88
Q
E
N
E
R
K
G
T
A
R
F
G
H
E
G
Dog
Lupus familis
XP_849179
417
46163
A48
Q
E
N
E
R
R
G
A
A
R
F
G
H
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
A48
Q
E
N
E
R
K
G
A
A
R
F
G
H
E
G
Rat
Rattus norvegicus
P12369
416
46104
A48
Q
E
N
E
R
K
G
A
A
R
F
G
H
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
Chicken
Gallus gallus
Q5ZM91
382
43332
D44
Q
L
C
T
V
R
P
D
R
P
M
G
F
L
R
Frog
Xenopus laevis
NP_001084637
402
45172
P48
Q
S
Q
S
Q
G
A
P
F
S
H
G
M
G
L
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S48
D
T
R
S
Q
D
G
S
G
A
A
A
K
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
T43
D
Y
A
V
E
Y
F
T
K
L
Q
S
E
R
P
Honey Bee
Apis mellifera
XP_392905
383
43849
Q53
L
R
E
S
R
Q
T
Q
L
I
Q
D
P
A
Q
Nematode Worm
Caenorhab. elegans
P30625
366
41449
L43
H
K
P
D
N
P
V
L
F
L
K
D
H
F
E
Sea Urchin
Strong. purpuratus
Q26619
369
41770
I44
A
K
L
Q
E
N
N
I
S
L
G
G
K
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
P52
A
F
L
K
A
R
E
P
E
F
K
A
K
N
I
Red Bread Mold
Neurospora crassa
Q01386
385
42138
N52
P
H
F
G
V
K
N
N
A
A
P
A
F
W
N
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
0
13.3
13.3
13.3
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
0
20
20
26.6
N.A.
6.6
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
0
7
0
7
19
44
13
7
19
0
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
7
0
7
0
7
0
0
0
13
0
0
0
% D
% Glu:
0
38
7
38
13
0
7
0
7
0
0
0
7
38
7
% E
% Phe:
0
7
7
0
0
0
7
0
13
7
38
0
13
7
0
% F
% Gly:
0
0
0
7
0
7
44
0
7
0
7
57
0
7
44
% G
% His:
7
7
0
0
0
0
0
0
0
0
7
0
44
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% I
% Lys:
0
13
0
7
0
38
0
0
7
0
13
0
19
0
0
% K
% Leu:
7
7
13
0
0
0
0
7
7
19
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
38
0
7
7
13
7
0
0
0
0
0
7
7
% N
% Pro:
7
0
7
0
0
7
7
13
0
7
7
0
7
0
7
% P
% Gln:
50
0
7
7
13
7
0
7
0
0
13
0
0
0
7
% Q
% Arg:
0
7
7
0
44
19
0
0
7
38
0
0
0
13
7
% R
% Ser:
0
7
0
19
0
0
0
7
7
7
0
7
0
0
0
% S
% Thr:
0
7
0
7
0
0
7
25
0
0
0
0
0
7
0
% T
% Val:
0
0
0
7
13
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _